Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus_repos |
| Phenotype | phenotype_ATM_minus_versus_BT_ATM_minus.cls#ATM_minus_versus_BT_ATM_minus_repos |
| Upregulated in class | BT_ATM_minus |
| GeneSet | BIOCARTA_THE CO-STIMULATORY SIGNAL DURING T-CELL ACTIVATION |
| Enrichment Score (ES) | -0.7215407 |
| Normalized Enrichment Score (NES) | -1.6430337 |
| Nominal p-value | 0.013513514 |
| FDR q-value | 0.20383075 |
| FWER p-Value | 0.972 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CD80 | 1427717_at 1432826_a_at 1440592_at 1451950_a_at 1454372_at 1457952_at | 1065 | 1.137 | 0.0109 | No | ||
| 2 | LCK | 1425396_a_at 1439145_at 1439146_s_at 1457917_at | 1423 | 0.930 | 0.0433 | No | ||
| 3 | GRB2 | 1418508_a_at 1449111_a_at | 3682 | 0.394 | -0.0391 | No | ||
| 4 | CD86 | 1420404_at 1449858_at | 9984 | 0.071 | -0.3229 | No | ||
| 5 | PTPN11 | 1421196_at 1427699_a_at 1451225_at | 10663 | 0.048 | -0.3513 | No | ||
| 6 | ICOSLG | 1419212_at 1426087_at | 12004 | 0.003 | -0.4123 | No | ||
| 7 | PIK3CA | 1423144_at 1429434_at 1429435_x_at 1440054_at 1453134_at 1460326_at | 15215 | -0.127 | -0.5521 | No | ||
| 8 | CTLA4 | 1419334_at | 18931 | -0.494 | -0.6957 | Yes | ||
| 9 | CD3G | 1419178_at | 19401 | -0.590 | -0.6862 | Yes | ||
| 10 | CD3D | 1422828_at | 19422 | -0.595 | -0.6560 | Yes | ||
| 11 | ICOS | 1421930_at 1421931_at 1436598_at | 20430 | -0.938 | -0.6529 | Yes | ||
| 12 | CD3E | 1422105_at 1445748_at | 21120 | -1.490 | -0.6064 | Yes | ||
| 13 | PIK3R1 | 1425514_at 1425515_at 1438682_at 1444591_at 1451737_at | 21161 | -1.529 | -0.5282 | Yes | ||
| 14 | ITK | 1417171_at 1430833_at 1452518_a_at 1456836_at 1457120_at | 21289 | -1.673 | -0.4465 | Yes | ||
| 15 | CD28 | 1417597_at 1437025_at 1443703_at | 21837 | -3.397 | -0.2938 | Yes | ||
| 16 | CD247 | 1420716_at 1426079_at 1426396_at 1428059_at 1428060_at 1438392_at 1452539_a_at | 21921 | -5.699 | 0.0006 | Yes |
